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Tender, warm, swollen joints; symmetrical pattern of affected joints; and joint inflammation often affecting the wrist and finger joints closest to the hand and sometimes other joints such as the neck, shoulders, elbows, hips, knees, ankles and feet. Other symptoms are fatigue, occasional fevers, a loss of energy and pain and stiffness lasting for

As RA progresses, the inflamed synovium invades and destroys the cartilage and bone within the joint. The surrounding muscles, ligaments and tendons that support and stabilize the joint become weak and unable to work normally. These effects lead to the pain and joint damage often seen in rheumatoid arthritis. Researchers studying rheumatoid arthrit

The four stages of rheumatoid arthritis are known as synovitis, pannus, fibrous ankylosis, and bony ankylosis - Stage I: Synovitis. During stage I, you may start having mild symptoms, including joint pain and joint stiffness. Stage II: Pannus. Stage III: Fibrous Ankylosis. Stage IV: Bony Ankylosis.